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Progesterone (P) Detection Kit (Immunochromatography)

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Introduction

[Product name] Progesterone (P) Detection Kit (Immunochromatography)

[Packaging Size]

5 tests/kit, 20 tests/kit

[Intended Use]

This product is used for the qualitative detection of progesterone (P) in human serum or plasma samples in vitro.
Progesterone is an important progestogen, belonging to steroid hormones, with a relative molecular weight of 314.5. It is mainly produced by the corpus luteum of the ovary and the placenta during pregnancy. It is the precursor of testosterone, estrogen and adrenal cortex hormones. The progesterone level produced during the follicular phase of normal males and females is very low, after secretion into blood, it is mainly bound to albumin and sex hormone binding protein and circulating in the body.

The main function of progesterone is to make the uterus prepared for the implantation of fertilized eggs and to maintain pregnancy. During the follicular phase of the menstrual cycle, the progesterone level is low. After ovulation, the progesterone produced by corpus luteum increases rapidly, and reaches the maximum concentration of 10ng/mL-20ng/mL in 5-7 days after ovulation. If not conceived, the corpus luteum atrophies during the last four days of the menstrual cycle and the progesterone concentration decreases to follicular phase. If conceived, the corpus luteum does not fade and continues to secrete progesterone, keeping it at levels equivalent to the medium luteal phase and continuing until the sixth week of pregnancy. During pregnancy, the placenta gradually becomes the main source of progesterone, and the concentration increases from 10ng/mL-50ng/mL in the first 3 months of pregnancy to 50ng/mL-280ng/mL in the 7-9 months. Clinical studies have shown that progesterone plays a role in promoting ovulation and maintaining the normal function of the corpus luteum in non-pregnant women. If the progesterone produced by corpus luteum is insufficient, it may indicate the corpus luteum function is insufficient, and the insufficient corpus luteum function is related to infertility and early miscarriage.

[Test Principles]

The progesterone (P) detection kit uses mouse anti-human progesterone antibody for tracer labeling, and uses P antigen coating as the test line. If there is a certain concentration of progesterone P in the sample to be tested, it will move to the test line under the action of chromatography. The progesterone P to be tested competes with the progesterone P antigen at the test line to bind the labeled mouse anti-human progesterone antibody, and the color of the test line becomes lighter. When the sample to be tested does not contain progesterone P antigen, the test line has the strongest color rendering. A colored band will appear in the region of control line regardless of whether the sample contains the antigen to be tested. The colored band in the region of control line is the standard for judging whether there are enough samples and whether the chromatography process is normal, and also serves as the internal control of the reagent.

[Storage Conditions and Shelf-life]

Storage Conditions: 4-30°C away from light and kept dry.
Shelf-life: 12 months
See label for production and expiry dates.
The test cassette should be used within 60 minutes after being taken out of the aluminum foil bag.

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